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Tuesday, June 30, 2009

Color Atlas of Pharmacology, 3rd Edition



Color Atlas of Pharmacology, 3rd Edition

Updated with the most important new substances and scientific developments, the third edition of The Color Atlas of Pharmacology makes it easier than ever for students, nurses, and practicing physicians to keep up with the latest developments in this constantly changing field. Featuring a user-friendly layout, jargon-free language, and more than 160 spectacular color charts and illustrations, the atlas is divided in to four, color-coded sections:
Part 1 - General pharmacology - includes descriptions of substance formulation, absorption, distribution, elimination, and molecular mechanisms of action Part 2 - Systems pharmacology - with special emphasis on the functional and therapeutic aspects of a wide range of medicinal agents Part 3 - Therapy of selected diseases - such as osteoporosis, acute myocardial infarction, migraine, asthma, tropical diseases, and many more Part 4 - Drug Index - helpfully listed by substance, generic, and brand names

Concise, portable, and packed with information, the third edition of The Color Atlas of Pharmacology is the most practical first-stop reference for today's busy healthcare professional.

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Lippincott's Illustrated Reviews: Pharmacology, 4th Edition



Lippincott's Illustrated Reviews: Pharmacology, 4th Edition

Lippincott's Illustrated Reviews: Pharmacology, Fourth Edition enables rapid review and assimilation of large amounts of complex information about the essentials of medical pharmacology. Clear, sequential pictures of mechanisms of action actually show students how drugs work, instead of just telling them. As in previous editions, the book features an outline format, over 500 full-color illustrations, cross-references to other volumes in the series, and over 125 review questions. Content has been thoroughly updated, and a new chapter covers toxicology. New to this edition will be a companion Website containing all of the illustrations, fully searchable text, and an interactive question bank.

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Bio-Chemistry




The inner life of the cell...amazing flash


An animated journey inside the cell



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Lehninger Principles of Biochemistry, Fourth Edition


Lehninger Principles of Biochemistry, Fourth Edition

This is a medium-sized heavyweight classic, updated, honest and useful for physicians. The authors do not make a fuss about the wealth of data available in biochemistry, keep a cool attitude overall and somehow manage to inspire lay readers. Physicians benefit from it a lot, since the dreaded detail of molecular pathology is described at an amazing level of medical awareness and even clinical relevance. Molecular models are clear enough for the busy practitioner who has little if any real interest in the arcane wireframes of those nevertheless current substances involved in prescriptions. The print is fine, and readable, the pagesetting is minimalist but useful, and the index is workable. As for the biochemical material, in the original text of Lehninger, everything has been carefully updated, in order not to spoil the reader with the usual Big Pharma nonsense. Incredible as it may sound this is an independent book even in the Age of Virtual News. Highly Reccommended. In conclusion, here we have a book we will not buy for the beauty of our reference desk, even in the age of the instant reference.

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Medicinal Chemistry


Medicinal Chemistry






Medicinal Chemistry
Publisher: New Age International English ISBN: 9788122423057 960 pages 2007 PDF 31 Mb

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Progress in Medicinal Chemistry : Volume 29


Progress in Medicinal Chemistry : Volume 29

Hardbound. The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey.

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Burger's Medicinal Chemistry and Drug Discovery, 6 Volumes Set



Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set

This new sixth edition of Burger's Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, an online version of this major reference work will offer updated content from the print edition and easy access. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.

The new sixth edition of Burger's Medicinal Chemistry and Drug Discovery is a Memorial Edition to Professor Alfred Burger who published this major reference work in the first edition as "Medicinal Chemistry" in two volumes in 1951. Dr. Burger's research focused on analgesics, antidepressants and chemotherapeutic agents. He is one of the few academicians to have a drug, designed and synthesized in his laboratories and brought to market. Dr. Burger's contribution to the fields of medicinal chemistry and drug discovery are well renowned and documented. He received the Louis Pasteur Medal of the Pasteur Institute and the American Chemical Society Smissman Award.

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Advanced Practical Medicinal Chemistry



Advanced Practical Medicinal Chemistry

The present compendium on Advanced Practical Medicinal Chemistry is designed specifically to serve as a text-cum-reference book not only intended for the advanced undergraduate and graduate students of Pharmacy specializing in pharmaceutical chemistry but also for the bulk-drug industrial researchers and academics who work intimately with medicinal compounds. It mainly comprises of four comprehensive chapters. First chapter is entirely devoted to Safety in Chemical Laboratory, which is an absolute must for each medicinal chemist. Second chapter is on Drug Synthesis and concentrates on three vital aspects, namely : conceptualization of a synthesis, reaction variants, and stereochemistry. Third chapter exclusively deals with Performing the Reactions and entails the wide range of latest laboratory techniques used in a good chemical laboratory to facilitate synthesis of drugs.

Fourth chapter is particularly focused and earmarked to Synthesis of Medicinal Compounds, and essentially include various cardinal aspects, such as :types of chemical reactions, organic name reactions (ONRs), and selected medicinal compounds. A galaxy of eighty carefully chosen medicinal compounds have been presented in an original unique style comprising of: chemical structure, synonym (s)/chemical name(s) theory chemicals required procedure precautions recrystallization theoretical yield/practical yield physical parameters uses, and questions for viva-voce.

It is hoped that Advanced Practical Medicinal Chemistry would certainly help to bridge existing gap and fill up the long needed vacuum in the synthesis of drugs in pharmaceutical chemistry departments, academics and bulk-drug industries, and may provide the basis for meaningful productive group discussions of synthetic problems on a broader perspective.

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Principles Of Organic Medicinal Chemistry




Principles of Organic Medicinal Chemistry

The book Principles of Organic Medicinal Chemistry describes the principles and concepts of chemistry, synthetic schemes, structure activity relationships, mechanism of action and clinical uses of carbon compounds in the light of modern trends. The book covers the syllabi of B.Pharmacy and M.Pharmacy courses of all Indian Universities.

This book comprises of 22 chapters. Chapter 1 gives an introduction to medicinal chemistry, Chapter 2 explain about the basics on principles of drug action and physicochemical properties of organic medicinal, substances are elaborated in Chapter 3. The concepts of Prodrugs and Drug metabolism are summarized in Chapter 4 and Chapter 5 respectively. Chapter 6 to Chapter 22 explains chemistry, properties, mechanism of action, structure activity relationships, chemistry of newer drugs and clinical uses of various therapeutic agents. At the end of book, a set of more than 200 essays and short questions and 225 objective questions with answers are strategically designed.

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Monday, June 29, 2009

Introduction to medicinal chemistry


Introduction to Medicinal Chemistry

Introduction to Medicinal Chemistry: How Drugs Act and Why by: Alex Gringauz
Publisher: Wiley-VCH ISBN: 0471185450 1996-12-27 Pages: 736 DJVU 23 MB

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.

Basic Considerations of Drug Activity.
Mechanisms of Drug Action.
Drug Metabolism and Inactivation.
Anticancer Drugs and Their Mechanism of Action.
Analgetics and Nonsteroidal Antiinflammatory Agents.
Antimicrobial Drugs I. Antimicrobial Drugs II.
Drugs Affecting Cholinergic Mechanisms.
Drugs Affecting Adrenergic Mechanisms.
Drugs and the Cardiovascular Diseases.
Drugs and the Cardiovascular Diseases II.
Psychoactive Drugs--Chemotherapy of the Mind.
Histamine Antagonists and Local Anesthetics.
Steroids.
New Developments and New Problems.
Index.


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