Friday, July 31, 2009
Quality Assurance in the Analytical Chemistry Laboratory
Quality Assurance in the Analytical Chemistry Laboratory
Quality Assurance in the Analytical Chemistry Laboratory
Publisher: Oxford University Press, USA ISBN: 0195162129 edition 2007 PDF 320 pages 2,4 mb
Analytical chemical results touch everyones lives can we eat the food? do I have a disease? did the defendant leave his DNA at the crime scene? should I invest in that gold mine? When a chemist measures something how do we know that the result is appropriate? What is fit for purpose in the context of analytical chemistry? Many manufacturing and service companies have embraced traditional statistical approaches to quality assurance, and these have been adopted by analytical chemistry laboratories. However the right chemical answer is never known, so there is not a direct parallel with the manufacture of ball bearings which can be measured and assessed. The customer of the analytical services relies on the quality assurance and quality control procedures adopted by the laboratory. It is the totality of the QA effort, perhaps first brought together in this text, that gives the customer confidence in the result. QA in the Analytical Chemistry Laboratory takes the reader through all aspects of QA, from the statistical basics and quality control tools to becoming accredited to international standards. The latest understanding of concepts such as measurement uncertainty and metrological traceability are explained for a working chemist or her client. How to design experiments to optimize an analytical process is included, together with the necessary statistics to analyze the results.
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Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products
Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products
Hardbound. In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given.
Features of this book:
• Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry
• Illustrates the different approaches available to attain robustness
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Passive Sampling Techniques in Environmental Monitoring, Volume 48
Passive Sampling Techniques in Environmental Monitoring, Volume 48
Monitoring pollutants in air, soil and water is a routine requirement in the workplace, and in the wider environment. Passive samplers can provide a representative picture of levels of pollutants over a period of time from days to months by measuring the average concentrations to which they have been exposed. Air monitors are widely used, for instance to measure the exposure of workers to volatile compounds, but also for monitoring the fate of pollutants in the atmosphere. Passive sampling devices are now becomining increasingly used to monitor pollutants in rivers, coastal waters and ground water where contamination results from sources such as domestic and industrial discharges, and the use of agrochemicals.
Passive Sampling Techniques in Environmental Monitoring provides a timely collection of information on a set of techniques that help monitor the quality of air, surface and ground waters. Passive sampling can provide an inexpensive means of obtaining a representative picture of quality over a period of time, even where levels of pollutants fluctuate due to discontinuous discharges or seasonal application of chemicals such as pesticides. Recent changes in legislation have increased the pressure to obtain better information than that provided by classical infrequent spot sampling.
Brought together in one source, this book looks at the performance of a range of devices for the passive sampling of metals, and of non-polar and polar organic chemicals in air and in water. The strengths and weaknesses and the range of applicability of the technology are considered.
* Comprehensive review of passive sampling - covering air, water and majority of available technologies in one volume
* Chapters written by international specialist experts
* Covers theory and applications, providing background information and guidelines for use in the field
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Instant Notes in Analytical Chemistry
Instant Notes in Analytical Chemistry
Instant Notes in Analytical Chemistry provides concise yet comprehensive coverage of analytical chemistry at an undergraduate level, providing easy access to the core information in the field. The book covers all the important areas of analytical chemistry in a format which is ideal for learning and rapid revision.
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Friday, July 24, 2009
Basic & Clinical Pharmacology
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RANG & DALE’S PHARMACOLOGY 6TH EDITION
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Wednesday, July 22, 2009
Spoken English Course Books & Softwares
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Speaking Hangman Free 1.0.0 Athena Soft,
Speaking Hangman is an educational game to practice and expand your English and Spanish vocabularies. The game is designed for people of any age above 7 years.
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Speech Syntheszier 5.0 Caltrox Educational Software
Download A great program for Children to learn English Speaking & Vocabulary. Speech Synthesizer 5.0 is a powerful Text-To-Speech voice synthesizer program that is extremely useful for learning English pronunciation and Vocabulary building. The Software runs on all Windows Systems and has adjustable. Free download of Speech Syntheszier 5.0, size 6.64 Mb. - Download
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Tuesday, July 21, 2009
ATLAS OF HUMAN ANATOMY F. NETTER
Editorial Reviews
Book Description
This pillar combines the exactitude and example of 325 Netter and Netter-style illustrations with updated aggregation to emit our ontogeny discernment of the some regions and systems of the brain, spinal cord, and periphery. Concise neuroscience pillar using Netter illustrations to particular key anatomy concepts and clinical correlations. The azygos prizewinning maker of illustrations of the troubled system, with broad up-to-date aggregation in a succinct and multipurpose format, reflecting underway discernment of the troubled system.
Book Info
Univ. of California, Irvine. Atlas featuring the New Dr. Frank Netter’s illustrations portrayal both regional and systemic neuroscience. Includes updated aggregation and newborn illustrations reflecting the ontogeny discernment of the mentality and spinal cord. Features newborn cross-sections finished the spinal cloth and the mentality stem. Softcover.
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GRAY’S ANATOMY: THE ANATOMICAL BASIS OF CLINICAL PRACTICE 39TH EDITION
Publisher: solon Livingstone
Number Of Pages: 1600
Publication Date: 2004-11-24
ISBN-10 / ASIN: 0443071683
ISBN-13 / EAN: 9780443071683
Binding: Hardcover
Book Description
Not since it prototypal publicised in 1858 has Gray’s Anatomy introduced so such conception to the concern of expression references. A aggroup of renowned clinicians, anatomists, and base scientists hit radically transformed this artist inventiveness to combine every of the newest expression noesis organized it by embody location to nonconvergent clinical training and additional some newborn opencast anatomy, radiologic anatomy, and microanatomy images to hands the delicate graphics that the aggregation is famous for. Although there are today some books titled “Gray’s Anatomy,” exclusive this 39th Edition carries on the genuine inheritance of the example text. And, exclusive this 39th Edition delivers so such pragmatic, clinically vital information. The termination is, erst again, the world’s expressed maker on manlike anatomy..
The Structures of Life
The Structures of Life
Publisher: National Institutes of Health 2007
ISBN/ASIN: B0015PS1XC
Number of pages: 66
Description:
A fascinating and easy-to-read book about the structures of life. From the contents: Proteins are the Body's Worker Molecules; X-Ray Crystallography: Art Marries Science; The World of NMR: Magnets, Radio Waves, and Detective Work; Structure-based Drug Design: From the Computer to the Clinic; Beyond Drug Design.
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Biochemistry, 2e
by Reginald Garrett and Charles Grisham
Publisher: Brooks Cole
ISBN/ASIN: 0495119121
ISBN-13: 9780495119128
Number of pages: 1216
Description:
Univ. of Virginia, Charlottesville. Textbook provides the fundamental principles governing the structure, function, and interactions or biological molecules. Specifically discusses the molecular components of cells, protein dynamics, metabolism and its regulation, and information transfer. Features chapter exercises and summaries.
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Saturday, July 18, 2009
Handbook of Stability Testing in Pharmaceutical Development: Regulations, Methodologies, and Best Practices
Handbook of Stability Testing in Pharmaceutical Development: Regulations, Methodologies, and Best Practices
A COMPREHENSIVE AND PRACTICAL GUIDE TO STABILITY TESTING IN PHARMACEUTICAL DEVELOPMENT
Stability testing is required to demonstrate that a pharmaceutical product meets its acceptance criteria throughout its shelf life and to gain regulatory approval for commercialization. Assessing drug product stability and safety can be quite complicated, and stability profile can impact many functional areas, including analytical testing, formulation development, toxicology, quality, and regulatory affairs.
Handbook of Stability Testing in Pharmaceutical Development: Regulations, Methodologies, and Best Practices is the first volume to cover all aspects of stability testing in pharmaceutical development. It presents a scientific understanding of regulations and balances methodologies and best practices. Comprising 17 chapters, it provides a wealth of resources for pharmaceutical companies, educational institutions, and manufacturing laboratories to use as either a supplementary text for stability training courses or as a reference book for pharmaceutical practitioners.
Topics covered include:
Latest regulations for stability testing, including cGMP requirements, ICH guidelines, and global guidances from WHO, ASEAN, EMRO, and other regions.
Post-approval considerations and regulatory filing strategies to support a global supply chain.
Methodologies, including development of a stability-indicating method, method validation, and transfer. This book also discusses physical stability, non-chromatographic methodologies, and spectroscopic applications.
Setting specifications, monitoring impurities, and establishing shelf-life of pharmaceutical products.
Data management, including stability reports, CMC, and discussion of out-of-specification (OOS) and out-of-trend (OOT).
USP-NF testing in support of stability.
Current industry best practices on stability operation, validation, and calibration of stability chambers including considerations for photo-stability testing.
Discussion of matrixing and bracketing to support reduced stability testing.
Overview of stability programs for biologics and drug-in-devices pharmaceutical products.
This collective work was written by a group of prominent international experts, who have been directly responsible for instituting industry best practices and establishing the current stability guidelines.
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Statistical Design and Analysis of Stability Studies
Statistical Design and Analysis of Stability Studies
The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates. Pharmaceutical companies conduct stability studies to characterize the degradation of drug products and to estimate drug shelf life. Illustrating how stability studies play an important role in drug safety and quality assurance, Statistical Design and Analysis of Stability Studies presents the principles and methodologies in the design and analysis of stability studies. After introducing the basic concepts of stability testing, the book focuses on short-term stability studies and reviews several methods for estimating drug expiration dating periods. It then compares some commonly employed study designs and discusses both fixed and random batch statistical analyses. Following a chapter on the statistical methods for stability analysis under a linear mixed effects model, the book examines stability analyses with discrete responses, multiple components, and frozen drug products. In addition, the author provides statistical methods for dissolution testing and explores current issues and recent developments in stability studies. To ensure the safety of consumers, professionals in the field must carry out stability studies to determine the reliability of drug products during their expiration period. This book provides the material necessary for you to perform stability designs and analyses in pharmaceutical research and development.
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Drug Stability: Principles and Practices
Drug Stability: Principles and Practices
Addressing concerns for patient welfare while protecting producer reputation, and providing a database for formulation of other products, this multiauthored reference blends fundamental theory and practical advice on drug product stability in scientific, technical, and regulatory environments, covering development of indicating assays, computer use, clinical trial materials, strategic planning, and packaging. Describing the documentation required to minimize the changes of regulatory citations, the book lists manufacturers of photostability testing chambers, stability system software, and laboratory information management systems for pharmaceutical applications.
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Thursday, July 16, 2009
Hugo and Russell's Pharmaceutical Microbiology
Hugo and Russell's Pharmaceutical Microbiology
Hugo and Russell's Pharmaceutical Microbiology, 7th edition by Stephen P. Denyer, Norman A. Hodges, Sean P. Gorman
Wiley-Blackwell 496 pages 2004-07-30 ISBN: 0632064676 PDF 3Mb
Completely revised and updated Pharmaceutical Microbiology continues to provide the essential resource for the 21st century pharmaceutical microbiologist...
"....a valuable resource for junior pharmacists grasping an appreciation of microbiology, microbiologists entering the pharmaceutical field, and undergraduate pharmacy students."
Journal of Antimicrobial Chemotherapy
".....highly readable. The content is comprehensive, with well-produced tables, diagrams and photographs, and is accessible through the extensive index."
Journal of Medical Microbiology
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World of Microbiology and Immunology
World of Microbiology and Immunology
This book is a new but excellent resource for high school students. I will be able to use it in both my regular and advanced biology classes. The book tackles some very tough topics and it is the first I have seen that allows experts to translate difficult topics into something useable and valuable to high school students. The topics are also very timely for students interested in how biology relates to the news.
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Handbook of Preformulation: Chemical, Biological, and Botanical Drugs
Handbook of Preformulation: Chemical, Biological, and Botanical Drugs
Sarfaraz K. Niazi (Author), "Handbook of Preformulation: Chemical, Biological, and Botanical Drugs"
Informa Healthcare 1 edition September 18, 2006 ISBN: 9780849371936 PDF English 6 Mb 446 pages
"Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance..."
Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this handbook provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.
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stability of drugs and dosage forms
stability of drugs and dosage forms
Sumie Yoshioka, Valentino J. Stella, "Stability of Drugs and Dosage Forms"
Springer; 1 edition (November 2000) ISBN: 0306464047 272 pages PDF 2,1 Mb
Drug products are complex mixtures of drugs and excipients and, as such, their chemical and physical stability kinetics are complex. This book discusses the stability of these dosage forms with preformulation studies through to the studies on the final products. The book is intended for graduate students, researchers and professionals in the field of Pharmaceutics and Pharmaceutical Chemistry.
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Tuesday, July 14, 2009
ENCYCLOPEDIA OF PHARMACEUTICAL TECHNOLOGY,THIRD EDITION
ENCYCLOPEDIA OF PHARMACEUTICAL TECHNOLOGY,THIRD EDITION
Presenting official and attractive articles on every aspects of take development, dosage, manufacturing, and regulation, this Third Edition enables the caregiver doc and initiate like to ready abreast of developments in this apace evolving and highly combative field. A secure meaning agency and unceasing consort for eld to come, the Third Edition module substance completely newborn entries that counterbalance grave issues in the earth much as the effect of genomics, biotechnology, and implants on take discovery, targeting, delivery, and formulation. In addition, it module come newborn restrictive issues, much as the changes in business regulations, and aborning bureau procedures.
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Monday, July 13, 2009
The Pharmacopoeia of the United States of America: Facsimile of the First Edition (1820)
The Pharmacopoeia of the United States of America: Facsimile of the First Edition (1820)
The Pharmacopoeia of the United States of America: (The United States Pharmacopoeia). By General Medical Convention, United States Pharmacopeial Convention Committee of Revision, United States Pharmacopœial Convention, General Convention for the Formation of the American Pharmacopoeia, National Convention for Revising the Pharmacopoeia Published by United States Pharmacopoeial Convention, Inc., 1820-1975., 1820
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European Pharmacopoeia, 4th edition
European Pharmacopoeia, 4th edition
The European Pharmacopoeia is a single reference work for the quality control of medicines in Europe. Several legal texts make the European Pharmacopoeia mandatory:A Convention on the Elaboration of a European Pharmacopoeia ratified in 2003 by 31 European countries and the European Union; European Union directives 2001/83/EC and 2001/82/EC,on medicines for human use and for veterinary use, respectively, maintain the mandatory character of European Pharmacopoeia specifications on medicines as regards their qualitative and quantitative composition and the tests to be carried out on these medicines, the raw materials used in production and the intermediates of synthesis. All producers of medicines or substances for pharmaceutical use therefore must apply the quality standards of the European Pharmacopoeia for the marketing and use of these products in Europe. The texts of the European Pharmacopoeia are legally binding and compliance is enforced by the administrative or juridical authorities. The national authorities of the member states are bound to apply them if necessary replacing any national monograph on the same subject.
The 4th Edition consists of an initial volume 2002 (4.0) and a collection of 8 non-cumulative supplements (4.1) published three times a year following the decisions of each session of the European Pharmacopoeia Commission. With supplement 4.6, the 4th Edition comprises 1750 specific monographs, 285 general methods illustrated by figures or chromatograms and 2140 reagents. Every 4 months a new volume enters into force.
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Wednesday, July 8, 2009
Indian Pharmacopoeia 1996
Indian Pharmacopoeia 1996
DETAILS
ISBN: 8190065831
Place of Publication: New Delhi
Publisher: The Controller of Publications
Edition: 1st ed.
Year of Publication: 2003
Physical Description: 140p.
Book Format: Hardcover
Language: English
SYNOPSIS
The latest edition of the Indian Pharmacopoeia was published in 1996. It was updated by additions and amendments introduced through addendum 2000. Under the Drugs and Cosmetics Act, 1940, the Indian Pharmacopoeia is the legally recognised book of standards for the quality of drug substances and their preparations included therein. In view of the rapid developments is pharmaceutical sciences and technology, it became necessary to make further changes in the existing compendium. Addendum 2002 amends as well as adds new drugs and preparations to the Indian pharmacopoeia 1996 with a view to keeping the pharmacopoeia updated to the extent possible. Besides amending the existing monographs and appendices, it contains 19 new monographs including monographs of 12 antiretroviral drugs and 7 formulations of these substances. A new appendix on residual solvents has been incorporated. Some monographs have undergone major amendments. The appendix on high performance liquid chromatography has been replaced with a new version which also includes the ion chromatography. The Addendum 2002 is a companion volume to the Indian pharmacopoeia which is indispensable for all concerned with the quality of drugs.
Instructions
* Burn the File into CD or DVD
* Then Install it from the CD
*CD must be placed in the CD / DVD drive when you need to use this software
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British Pharmacopoeia 2009
British Pharmacopoeia 2009
"The British Pharmacopoeia" ("BP") 2009 is the authoritative, current collection of standards for UK medicinal substances and the official source of all UK pharmaceutical quality standards. It is an essential reference for anyone involved in pharmaceutical research, development, manufacture and testing, and plays a vital role in ensuring that all medicinal substances on the UK market meet standards of safety, quality and efficacy.The "BP" comprises monographs, which set out the mandatory standards for active substances, excipients and formulated preparations, together with supporting General Notices, Appendices (test methods, reagents, etc) and Reference Spectra. Detailed information and guidance on various aspects of current pharmacopoeial policy and practice are provided in the Supplementary Chapters of the "BP".The "BP" is supplied in a variety of formats designed for ease of use and a wide range of applications. The hard copy edition comprises a five-volume boxed set containing the "BP" in four volumes and the "BP" (Veterinary) volume, plus single user access to the "BP" Online, the dedicated BP website. The online format is easy to network, allowing access for a specified number of users or across an entire organisation site.Following registration - using the ID code supplied with the hard copy - customers will be granted a single user licence to access BP on-line and will have the option to receive the CD-ROM, which contains the whole of the current "British Pharmacopoeia".It is effective as of 1 January 2009. It includes: a significant number of new UK monographs; all "European Pharmacopoeia 6th Edition" material up to and including "Supplement 6.2" integrated into the text of "BP 2009"; new and revised monographs for Complementary, Herbal and Homoeopathic medicines with their own section in Volume III; and networking with full technical support from TSO, the publisher of the "BP". The on-line version delivers the complete text of the "British Pharmacopoeia and European Pharmacopoeia" standards to your PC. The new features include an alphabetical index, user-friendly search interface design, and a facility to create a 'My BP' section." British Pharmacopoeia 2009" eBook - "The complete British Pharmacopoeia 2009" is now available exclusively to "BP 2009" purchasers in an innovative new format. The eBook is greatly suited to this large reference text making the information contained within it available to all of those who wish to access it on the move and away from their desks.British Pharmacopoeia 2009 Concurrent Licence (Online) - "The British Pharmacopoeia" is available as a network licence which can be used on a concurrent user basis. It allows a designated number of staff simultaneous access to the online version of the "British Pharmacopoeia 2009". Once set up, your workforce can then start using the BP at their convenience.
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Monday, July 6, 2009
Modern Industrial Microbiology and Biotechnology
Modern Industrial Microbiology and Biotechnology
by Nduka Okafor (Author)
Product Details
* Hardcover: 539 pages
* Publisher: Science Publishers; 1 edition (March 30, 2007)
* Language: English
* ISBN-10: 1578084342
Book Description
This book is directed towards undergraduates and beginning graduate students in microbiology, food science and chemical engineering. Those studying pharmacy, biochemistry and general biology will find it of interest. The section on waste disposal will be of interest to civil engineering and public health students and practitioners. For the benefit of those students who may be unfamiliar with the basic biological assumptions underlying industrial microbiology, such as students of chemical and civil engineering, elements of biology and microbiology are introduced. The new elements which have necessitated the shift in paradigm in industrial microbiology such as bioinformatics, genomics, proteomics, site-directed mutation, metabolic engineering, the human genome project and others are also introduced and their relevance to industrial microbiology and biotechnology indicated. As many references as space will permit are included. The various applications of industrial microbiology are covered broadly, and the chapters are grouped to reflect these applications. The emphasis throughout, however, is on the physiological, biochemical principles, and where possible, the genomic principles behind these applications.
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Veterinary Microbiology
Veterinary Microbiology
by Dwight C. Hirsh (Editor), Yuan Chung Zee (Editor)
Product Details
* Paperback: 479 pages
* Publisher: Blackwell Publishing Professional; 2nd edition (January 15, 1999)
* Language: English
* ISBN-10: 0865425434
Book Description
The most recent revision of this comprehensive text covers the bacterial, fungal, and viral pathogenic agents that are significant causes of animal disease. The focus includes pathogenic mechanisms and processes in infectious diseases; methods of diagnosis; and principles of resistance, prevention, and therapy.
In addition to serving as a resource for veterinary students, Veterinary Microbiology, Second Edition also serves as a convenient reference for veterinarians and veterinary scientists whose main line of activity and expertise is outside the areas of microbiology.
Veterinary Microbiology, Second Edition is now organized in four sections according to the most appropriate methods of instruction:
Part I deals with the general characteristics of the host– parasite relationship, laboratory diagnosis of conditions involving an infectious etiology, antimicrobial treatment, and prevention of infectious disease.
Part II (Bacteria and Fungi) and Part III (viruses) present the infectious agents that affect the veterinary species. The chapters dealing with the bacterial agents are grouped mainly by morphology, and their gram-staining characteristics. The fungal agents are grouped mainly by morphologic characteristics (yeast, mold). The viruses are grouped along taxonomic grounds.
Part IV, an enhancement new to this edition, deals with the infectious agents in the context of the host. This section is organized by organ system. Each organ system is discussed first as a microbial habitat, followed by discussion of those infectious agents that mainly affect that particular system.
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Encyclopedia of Microbiology
Encyclopedia of Microbiology
by Moselio Schaechter (Author, Editor)
Product Details
* Hardcover: 4600 pages
* Publisher: Academic Pr; 3 edition (April 15, 2009)
* Language: English
* ISBN-10: 012373939X
Book Description
An all-encompassing reference to meet the needs of the diverse number of disciplines dealing with microorganisms
This is a comprehensive and creative collection of reviews of every imaginable aspect of the microbial world from ABC transport to zoonoses. The scope, detail and organization of this four-volume set is truly remarkable. The editor provides the reader with a limitless supply of reference material for teaching purposes, research, or historical perspective. This encyclopedia is an all-encompassing reference to meet the needs of the diverse number of disciplines dealing with microorganisms, including public health and agricultural and industrial microbiology, to name a few. To this end, the text is a huge success as the editor has provided a balanced compendium of topics in which no discipline is short-changed. The organization of this book is a strong feature. .... The list of contributors is a veritable who's who in the field of microbiology, truly reflecting a world-wide consortium of authors. The complexity and array of subject matter covered in this book is (in the current vernacular) awesome! Once the secret is out, this text should find itself on the office shelves of all professional microbiologists and in the library of every academic microbiology department throughout the world.
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Sunday, July 5, 2009
Peptide Companion - Software
Peptide Companion - Software
Calculates:
•Molecular weights
•Elemental analysis results
•Amino acid composition
•Mass spectral fragmentation
Predicts:
•HPLC behavior of peptides
•Difficult sequences to synthesize
•Conformational parameters of peptides/proteins
•Enzymatic or chemical degradation
•Composition of peptide or nonpeptide library
•Amino acid composition from M.W.
Additional features:
•Finds problems in mass spectra
•Evaluates peptide content in lyophilizate based on elemental analysis
•Translates one letter code to/from three letter code
•Serves as database of hundreds of peptides
•Serves as database of protecting groups and other abbreviations
•Understands peptide language
Requires Windows 3.1, 95, 98, 2000, NT, or a system capable of running Windows programs.
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FieldAlign Ver 1.0.2
FieldAlign™ is ideal for visual inspection of alignments of actives from different series and identifying shared field features or pharmacophores, providing a qualitative indication of field SAR. FieldAlign is useful at the early stage of library design as small virtual libraries can be aligned to an active template and the chemist can select those scaffolds and monomers which together best match the active field template. FieldAlign can also be used as an aid to lead optimisation: iteratively changing molecules in FieldAlign and observing the alignments and field patterns can provide powerful insights into the direction that your chemistry should go. It is also invaluable for overlaying series of molecules prior to 3D QSAR studies where a good alignment of the molecules is critical for obtaining meaningful models.
FieldAlign™ is available as a Linux or Windows GUI program. A Linux command line version is also available which can be readily customized by expert users.
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Herb Navigator
User friendly revolutionary program that will allow you quickly and easily improve the accuracy of your clinical observations, diag- nosis and herbal prescriptions.
With a few clicks of the mouse, you can quickly and easily see more clearly the possibilities and best use of interconnected formulas, conditions, and actions.
•Over 140 herbs and over 400 specific ailments are referenced
•Search by indication
•Unique search by multiple actions
•The program offers you the ability to add your own data.
•Preparation methods are given for each herb
•Adult dosage ranges for all appropriate preparations are given
Oxford Dictionary of Biochemistry and Molecular Biology Second Edition
Oxford Dictionary of Biochemistry and Molecular Biology Second Edition
Oxford University Press, USA ISBN:0198529171 2006-08-24 PDF 736 pages 5.7 MB
The Oxford Dictionary of Biochemistry and Molecular Biology provides a comprehensive survey of current biochemistry and molecular biology. Over the last few years, the language of Biochemistry and Molecular Biology has expanded enormously to the extent that few scientists can expect to be familiar with all aspects of it. This is partly due to the Genome projects and the successive -omics projects which have provided comprehensive information about genes, the functions of gene products, and cellular processes. At the same time, terms from other subject areas appear increasingly in the biochemical literature. The popular Dictionary has been comprehensively reviewed and updated to include many important new concepts and words. The entries are short but informative, providing up-to-date information on a broad range of topics, including definitions for selected terms from Bioinformatics, Biophysics, Cell Biology, Chemistry, Genetics, Immunology, Mathematics, Microbiology, Pharmacology, Systems Biology, and Toxicology. There are over 21,000 main entries, which give details of biochemical substances and the processes in which they are involved, define methods and concepts in molecular biology, and give definitions of biochemical symbols and abbreviations. It points out pitfalls where terms are often confused. It explains the precise syntax of biochemical terms, such as Greek letters and other formatting, which are lost when searching the Internet. In addition the dictionary is illustrated with over 900 chemical structures.
The Oxford Dictionary of Biochemistry and Molecular Biology will serve as an invaluable reference for biochemists and molecular biologists seeking information outside their own fields, and for those wishing to revisit fundamental principles.
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Saturday, July 4, 2009
Pediatric Radiology: The Learning File CD-ROM - American College of Radiology (ACR)
Pediatric Radiology: The Learning File CD-ROM - American College of Radiology (ACR)
The Learning File Web currently contains 16882 images in 3974 cases and self evaluation in 8 different system.
Download: Part 1
Virtual Plastic Surgery Software 1.3
Virtual Plastic Surgery Software 1.3
Modify photos to simulate virtual plastic surgery results."
The VPSS is a simple to use, yet powerful photo warping software that will let you modify photos to simulate virtual plastic surgery results on anyone's face and body. As a specific purpose software, we developed a custom and convenient interface more suited for virtual plastic surgery simulation than anything you will find on general purpose, thousand dollars traditional software suits.
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Friday, July 3, 2009
Pharmacy Practice
Pharmacy Practice
Today's pharmaceutical services are patient-oriented rather than drug-oriented. This shift towards patient-centred care comes at a time when healthcare is delivered by an integrated team of health workers. Effective pharmacy practice requires an understanding of the social context within which pharmacy is practised, recognising the particular needs and circumstances of the users of pharmaceutical services and of pharmacy's place within health service provision. Designed for undergraduate and postgraduate pharmacists, Pharmacy Practice provides a background to the social context of pharmacy including:
* the development of pharmacy practice
* international dimensions of pharmacy practice
* health, illness, and medicines use
* professional practice
* meeting the pharmaceutical care needs of specific populations
* measuring and regulating medicines use
* research methods, evaluation, audit and clinical governance
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Encyclopedia of Clinical Pharmacy
Encyclopedia of Clinical Pharmacy
This reference presents the latest procedures, practice guidelines, consensus documents, technological strategies, and regulatory standards for optimal pharmaceutical care--offering summaries for practical applications in a variety of clinical settings, including community and health-system pharmacies, clinics, hospice and long-term care facilities, government agencies, and pharmaceutical research and development organizations.
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Separation and Purification Techniques in Biotechnology
Separation and Purification Techniques in Biotechnology
This book describes separation and purification techniques--adsorption, ion exchange and liquid chromatography on solid supports--used for fermentation and biochemical feedstreams. Emphasis is placed on basic sorption theory, laboratory evaluation techniques, sorptive materials and their characteristics, scale-up of laboratory techniques, and their industrial applications. Each chapter contains specific examples illustrating the use of purification techniques in biotechnology processes.
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Molecular Biology and Biotechnology
Molecular Biology and Biotechnology
As a textbook, Molecular Biology and Biotechnology has always been immensely popular. Now in its fourth edition, it has been completely revised and updated to provide a comprehensive overview of the area, and to reflect all the latest developments. Written by recognised experts, each of the nineteen chapters describes a specific subject area relevant to the subject of biotechnology. The impressive breadth of coverage takes into account both molecular biology and industrial applications and aims to identify the impact that molecular biology has had on the development of biotechnology. Presenting information in an easily assimilated form, Molecular Biology and Biotechnology makes an ideal undergraduate text. It will be of particular interest to students of biology and chemistry, as well as to scientists from outside the field requiring a rapid introduction to the subject.
Pharmaceutical Biotechnology
Pharmaceutical Biotechnology
The textbook on Pharmaceutical Biotechnology provides comprehensively the fundamental concepts and principles in Biotechnology to expatiate and substantiate its numerous modern applications with regard to the spectacular development in the Pharmaceutical Industry. In a broader perspective, the students studying Biotechnology at undergraduate and postgraduate levels shall be grossly benefited by its well-planned systematically developed, structured, illustrated, expanded, elaborated, and profusely exemplified subject matter.It essentially comprise five major chapters, namely: Immunology and Immunological Preparations; Genetic Recombination; Antibiotics; Microbial Transformations; and Enzyme Immobilization. Besides, there are five auxiliary chapters, namely, Advent of Biotechnology; Biosensor Technology; Bioinformatics and Data Mining; Regulatory Issues in Biotechnology; and Safety in Biotechnology, which have been specifically included so as to stimulate the students, interest and broaden their horizon of knowledge and wisdom.The authors earnestly believe that the wide coverage of various topics mentioned above would certainly render Pharmaceutical Biotechnology to serve as an exclusive source of information`s, ideas, inspirations towards research, and finding newer possible practical solutions to problems encountered in the ever green pasture using knowledge of Biotechnology in the Pharmaceutical Industry. Contents Immunology and Immunological Preparations
Genetic Recombination
Microbial Transformations
Enzyme Immobilization
Advent of Biotechnology
Biosensor Technology
Bioinformatics and Data Mining
Regulatory Issues in Biotechnology
Safety in Biotechnology
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Modern Industrial Microbiology and Biotechnology
Modern Industrial Microbiology and Biotechnology
This book is directed towards undergraduates and beginning graduate students in microbiology, food science and chemical engineering. Those studying pharmacy, biochemistry and general biology will find it of interest. The section on waste disposal will be of interest to civil engineering and public health students and practitioners. For the benefit of those students who may be unfamiliar with the basic biological assumptions underlying industrial microbiology, such as students of chemical and civil engineering, elements of biology and microbiology are introduced. The new elements which have necessitated the shift in paradigm in industrial microbiology such as bioinformatics, genomics, proteomics, site-directed mutation, metabolic engineering, the human genome project and others are also introduced and their relevance to industrial microbiology and biotechnology indicated. As many references as space will permit are included. The various applications of industrial microbiology are covered broadly, and the chapters are grouped to reflect these applications. The emphasis throughout, however, is on the physiological, biochemical principles, and where possible, the genomic principles behind these applications.
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Wednesday, July 1, 2009
Healthcare Management Dictionary
Healthcare Management Dictionary
A comprehensive reference book to help understand clinical and management terms, acronyms and jargon commonly used within the NHS. It includes terms used throughout Primary, Secondary and Social Health Care, and general management terms used throughout the public and private sectors. Website links are provided for further information. This book is aimed at all healthcare professionals and everyone is contact with the NHS and health industry, including academics, pharmaceutical company staff, social services managers and journalists.
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Dictionary for Clinical Trials
Dictionary for Clinical Trials
As a result of the expansion in the area of pharmaceutical medicine there is an ever-increasing need for educational resources. The Dictionary of Clinical Trials, Second Edition comprehensively explains the 3000 words and short phrases commonly used when designing, running, analysing and reporting clinical trials.
This book is a quick, pocket reference tool to understand the common and less well-used terms within the discipline of clinical trials, and provides an alternative to the textbooks available. Terms are heavily cross-referenced, which helps the reader to understand how terms fit into the broad picture of clinical trials.
Wide ranging, brief, pragmatic explanations of clinical trial terminology
Scope includes medical, statistical, epidemiological, ethical, regulatory and data management terminology
Thoroughly revised and expanded - increase of 280 terms from First Edition, reference to Cochrane included
From the reviews of the First Edition:
"This invaluable text explains the majority of clinical trial terms, in alphabetical order, that are likely to be found in clinical trial protocols, reports, regulatory guidelines, and published manuscripts... Fully comprehensive - provides definitions of clinical trial terms in one complete volume... Includes extensive use of graphs throughout." LA DOC STI
"...covers a range of subject matter, with emphasis on medical, statistical, epidemiological and ethical terms... a useful adjunct to standard clinical trial texts... a reference source to keep within easy reach." TALANTA
The Dictionary of Clinical Trials, Second Edition is a ‘must-have’ for all pharmaceutical companies who conduct a lot of clinical trials, in all or one therapeutic area. The book is also of interest for public health and health science workers, and for contract research organisations and departments of medicine, where medics are involved with clinical trials.
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Litt's Drug Eruption Reference Manual Including Drug Interactions, 14th Edition
Litt's Drug Eruption Reference Manual Including Drug Interactions, 14th Edition
Litt's Drug Eruption Reference Manual, 14th edition, has been updated and improved and incorporates dermatological drug eruptions plus reactions affecting the nails, hair, nails, eyes and mucosal.. This valuable resource also includes herbal and supplements reactions, in addition to hazardous drug-drug interactions. This book is a must have for all dermatologists, general practitioners and those working in emergency medicine.
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Medicines, 6th ed
Medicines, 6th ed
This is the sixth edition of Medicines: The Comprehensive Guide – the most popular and best-selling dictionary-style reference source-book for the range of medicines, along with possible side-effects, that is available in the UK today. Previous editions of this book have sold almost two million copies. The text has been extensively revised – to take account of the many new drugs, both generic and proprietary, as well as entire new drug groups, that have been developed and marketed since publication of the fifth edition in 2000. Changes in details of those medicines that remain on the market are also included. Requests from the public have led to the inclusion in this edition of expanded warnings about possible interactions between drugs with other medicines – especially those that can be obtained without a prescription –herbal remedies and nutritional supplements. There is also an expanded glossary of medical terms, which hopefully readers will find useful in understanding some of the more technical terms.
Elsevier's Dictionary of Vitamins and Pharmacochemistry
Elsevier's Dictionary of Vitamins and Pharmacochemistry
The dictionary will contain terms covering the following fields and subfields: Vitamin Technology: Vitamin biochemistry / Physiology; Origin of vitamins: natural, synthetic; Fat-soluble vitamins; Water-soluble vitamins; Vitamins as antioxidants; Vitamin deficiencies / Hypervitaminosis - Enzymes/Proteins: Biotechnology as applied biological science aimed at industrial exploitation - Hormones: Biochemistry; Physiology - Pharmaceutical Chemistry / Pharmaceutical Technology / Pharmaceutical Processes: Conception of the active principles; Structural analysis; Antibiotics and their way of action; Biochemistry; The Drug / The Medicament: Definition, origin, way of action; Biochemistry - Medical Aspects in the languages English, German, French and Portuguese.
*An important resource for pharmacologists, pharmaceutists and medical doctors
*Includes definitions in several prominent languages (English, German, French, Portuguese)
*Covers subfields of Vitamin Technology, Enzymes/Proteins, Hormones, Pharmaceutical Chemistry, Pharmaceutical Technology, Pharmaceutical Processes, and more.
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