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Sunday, December 2, 2012

Microwave Assisted Organic Synthesis


Microwave Assisted Organic Synthesis

Microwave-assisted organic chemistry has during the last years moved from being an obscurity in the laboratory environment to be an invaluable tool within chemistry research. Although the first reports on microwave-assisted organic synthesis dates back as far as 1986, the breakthrough of the technique as a routine tool in synthesis has been slow. The main reason has been difficulties in conquering the forces of the flame, i.e. there has been a lack of dedicated equipment available to perform chemistry using microwave irradiation. This lack of dedicated equipment led to the use of domestic appliances, leading to very unpredictable and sometimes devastating results. It also gave the technique an aura of black art. However, with the introduction of dedicated equipment, novel, interesting, reproducible chemistry has been and is continuously performed

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