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Sunday, August 29, 2010

xPharm: The Comprehensive Pharmacology Reference


xPharm: The Comprehensive Pharmacology Reference

xPharm, a state of the art, online, comprehensive pharmacology reference work. xPharm is comprised of four searchable and highly interlinked databases covering molecular Targets, including receptors, enzymes, transporters and ion channels, chemical Agents, including both drugs and endogenous compounds, clinical Disorders, and basic pharmacological Principles.

xPharm is designed to exploit the advantages provided by online publishing in allowing a user to customize information retrieval by quickly identifying and linking data from a large reference work. In addition, electronic publishing permits timely updates, which are not possible with printed material. xPharm is unique in that it was constructed from the beginning as an online reference work, rather than trying to adapt a print product to an online venue.

The idea for four databases was driven by the fact that Agents, including drugs, which are the core of pharmacology, act at molecular Targets to treat Disorders. The Principles database is included as a repository of information fundamental to the discipline but generally independent of the chemical entity, site of action, or clinical use. Each xPharm record is composed and reviewed by experts and the information placed within a highly structured format consistent within each database.

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